Case Study Protocol

  • Patients were required to have a wound with no progress in at least 2 weeks under conventional treatment.
  • Patients were seen 1 to 2 times per week.
  • Debridement occurred at the initial visit, if required, and then limited there after.
  • MIRRAGEN® Advanced Wound Matrix was applied to the wound and covered with a cover dressing.
  • On subsequent visits, the MIRRAGEN® material was simply washed off with a sterile saline rinse to expose the wound for photos and measurements.
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MIRRAGEN® Case Review
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Diabetic Foot Ulcer

Venous Leg Ulcer
​Healing rate: 25.3 mm2/day    Healing time: 33 days
Wound size: 38 × 22 × 8 mm
Age of wound when treatment started: > 1 year
Subject: 52/male. Insulin dependent diabetic, peripheral neuropathy, hypertension, renal failure on hemodialysis; history of chronic foot wounds.
Healing rate: 14.3 mm2/day    Healing time: 103 days
Wound size: 49 × 30 × 3 mm
Age of wound when treatment started: ~ 3 months 
Subject: 62/male. Non-insulin dependent diabetes, venous insufficiency, peripheral neuropathy, HTN, CHF, COPD, asthma.

​Pressure Ulcer

​Healing rate: 67.9 mm2/day    Healing time: 159 days
Wound size: 135 × 80 × 10 mm w/70-mm undermining at 3 o’clock
Age of wound when treatment started: 4 months
Subject: 44/male. Paraplegic. Frail with contractures and muscle wasting; tube fed, incontinent, dependent for all care.

Deep Tissue Injury (Traumatic)

​Healing rate: 5.4 mm2/day    Healing time: 93 days
Wound size: 25 × 20 × 3 mm w/undermining
Age of wound when treatment started: 4 months
Subject: 68/female. Diabetes, peripheral neuropathy, and venous insufficiency. Necrotic tissue was treated with moistened MIRRAGEN™ advanced wound matrix for 2 days to soften and loosen necrotic tissue for easy removal.

Venous Stasis Ulcer

​Healing rate: 39 mm2/day    Healing time: 127 days
Wound size: 66 × 75 × 25 mm
Age of wound when treatment started: ~ 3–4 months
Subject: 43/female. Presented with extreme wound odor that resolved after 3 visits. Morbid obesity, hypertension, hypothyroidism, lymphedema, and venous insufficiency; denies other health problems.

Traumatic Injury

​Healing rate: 7 mm2/day    Healing time: 210 days
Wound size: 30 × 30 × 30 mm
Age of wound when treatment started: ~ 2 months
Subject: 70/female. Obesity, diabetes, PVD, PAD, neuropathy, heart disease, and venous insufficiency. History of smoking, chronic foot wounds and recurring infections.