MIRRAGEN® Advanced Wound Matrix was tested in a clinically relevant porcine wound model under GLP conditions.
Dermal Wounds: 4 cm x 4 cm full-thickness and partial thickness
Treatments (n=6 each)
MIRRAGEN® Advanced Wound Matrix
Synthetic polymer fiber
Collagen+Ag fiber
Wound Closure Time 1
Full Thickness Wounds @ Day 29 1
Synthetic Polymer Fiber
Collagen + Ag Fiber
At Day 29 MIRRAGEN® Advanced Wound Matrix wound was fully closed, whereas the synthetic polymer fiber and collagen fiber treated wounds were still open. 1
Full Thickness Wound Histology at Day 56 (Hematoxylin & Eosin) 1
Synthetic Polymer Fiber
Collagen + Ag Fiber
At Day 56 MIRRAGEN® Advanced Wound Matrix showed the least inflammation and most mature granulation tissue compared to the synthetic polymer fiber and collagen fiber treated wounds. 1
Conclusions 1
Full and partial thickness wounds covered with the MIRRAGEN® Advanced Wound Matrix healed in less time and more completely compared to similar devices in head-to-head testing.
1 Data on file. Animal data may not be reflective of human clinical experience. Images selected are representative of study animals and wounds.