Yucatan Miniature Porcine Wound Healing Study 

MIRRAGEN® Advanced Wound Matrix was tested in a clinically relevant porcine wound model under GLP conditions.

• Dermal Wounds: 4 cm x 4 cm full-thickness and partial thickness  
• Treatments (n=6 each)
  • MIRRAGEN® Advanced Wound Matrix
  • Synthetic polymer fiber
  • Collagen+Ag fiber ​

Wound Closure Time 1

Full Thickness Wounds @ Day 29 1

​Synthetic Polymer ​Fiber​ ​

​Collagen + Ag Fiber​

At Day 29 MIRRAGEN® Advanced Wound Matrix wound was fully closed, whereas the synthetic polymer fiber and collagen fiber treated wounds were still open. 1  

Full Thickness Wound Histology at Day 56 (Hematoxylin & Eosin)​ 1

​​Synthetic Polymer Fiber​

​Collagen + Ag Fiber

At Day 56 MIRRAGEN® Advanced Wound Matrix showed the least inflammation and most mature granulation tissue compared to the synthetic polymer fiber and collagen fiber treated wounds. 1  

Conclusions 1

• Full and partial thickness wounds covered with the MIRRAGEN® Advanced Wound Matrix healed in less time and more completely compared to similar devices in head-to-head testing.​​

1 Data on file. Animal data may not be reflective of human clinical experience. Images selected are representative of study animals and wounds.